Discovery of Boolean metabolic networks: integer linear programming based approach

BACKGROUND: Traditional drug discovery methods focused on the efficacy of drugs rather than their toxicity. However, toxicity and/or lack of efficacy are produced when unintended targets are affected in metabolic networks. Thus, identification of biological targets which can be manipulated to produc...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Yushan, Jiang, Hao, Ching, Wai-Ki, Cheng, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907190/
https://www.ncbi.nlm.nih.gov/pubmed/29671395
http://dx.doi.org/10.1186/s12918-018-0528-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907190/
https://www.ncbi.nlm.nih.gov/pubmed/29671395
http://dx.doi.org/10.1186/s12918-018-0528-3

Ejemplares similares