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Measuring phenotype-phenotype similarity through the interactome

BACKGROUND: Recently, measuring phenotype similarity began to play an important role in disease diagnosis. Researchers have begun to pay attention to develop phenotype similarity measurement. However, existing methods ignore the interactions between phenotype-associated proteins, which may lead to i...

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Detalles Bibliográficos
Autores principales: Peng, Jiajie, Hui, Weiwei, Shang, Xuequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907215/
https://www.ncbi.nlm.nih.gov/pubmed/29671400
http://dx.doi.org/10.1186/s12859-018-2102-9