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Young and Especially Senescent Endothelial Microvesicles Produce NADPH: The Fuel for Their Antioxidant Machinery

In a previous study, we demonstrated that endothelial microvesicles (eMVs) have a well-developed enzymatic team involved in reactive oxygen species detoxification. In the present paper, we demonstrate that eMVs can synthesize the reducing power (NAD(P)H) that nourishes this enzymatic team, especiall...

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Detalles Bibliográficos
Autores principales: Bodega, Guillermo, Alique, Matilde, Bohórquez, Lourdes, Morán, Miriam, Magro, Luis, Puebla, Lilian, Ciordia, Sergio, Mena, María C., Arza, Elvira, Ramírez, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907394/
https://www.ncbi.nlm.nih.gov/pubmed/29849879
http://dx.doi.org/10.1155/2018/3183794