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Effects of senolytic drugs on human mesenchymal stromal cells

BACKGROUND: Senolytic drugs are thought to target senescent cells and might thereby rejuvenate tissues. In fact, such compounds were suggested to increase health and lifespan in various murine aging models. So far, effects of senolytic drugs have not been analysed during replicative senescence of hu...

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Detalles Bibliográficos
Autores principales: Grezella, Clara, Fernandez-Rebollo, Eduardo, Franzen, Julia, Ventura Ferreira, Mónica Sofia, Beier, Fabian, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907463/
https://www.ncbi.nlm.nih.gov/pubmed/29669575
http://dx.doi.org/10.1186/s13287-018-0857-6