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MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1

BACKGROUND: The miRNA cluster miR-17-92 is known to act as an oncogene in various cancers. Members of this cluster were also found to be involved in some other pathological process, such as steatosis, which is a pivotal event in the initiation and progression of nonalcoholic fatty liver disease (NAF...

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Detalles Bibliográficos
Autores principales: Gong, Ruijie, Lv, Xiaofei, Liu, Fengqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907481/
https://www.ncbi.nlm.nih.gov/pubmed/29721023
http://dx.doi.org/10.1186/s11658-018-0083-3