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Decreased cAMP Level and Decreased Downregulation of β(1)‐Adrenoceptor Expression in Therapeutic Hypothermia‐Resuscitated Myocardium Are Associated With Improved Post‐Resuscitation Myocardial Function

BACKGROUND: Epinephrine administered during cardiopulmonary resuscitation (CPR) is associated with severe post‐resuscitation myocardial dysfunction. We previously demonstrated that therapeutic hypothermia reduced the severity of post‐resuscitation myocardial dysfunction caused by epinephrine; howeve...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Hua, Tianfeng, Li, Hao, Wu, Xiaobo, Bradley, Jennifer, Peberdy, Mary Ann, Ornato, Joseph P., Tang, Wanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907536/
https://www.ncbi.nlm.nih.gov/pubmed/29572320
http://dx.doi.org/10.1161/JAHA.117.006573