Experimental Right Ventricular Hypertension Induces Regional β1‐Integrin–Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling

BACKGROUND: Development of right ventricular (RV) hypertension eventually contributes to RV and left ventricular (LV) myocardial fibrosis and dysfunction. The molecular mechanisms are not fully elucidated. METHODS AND RESULTS: Pulmonary artery banding was used to induce RV hypertension in rats in vi...

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Detalles Bibliográficos
Autores principales: Sun, Mei, Ishii, Ryo, Okumura, Kenichi, Krauszman, Adrienn, Breitling, Siegfried, Gomez, Olga, Hinek, Aleksander, Boo, Stellar, Hinz, Boris, Connelly, Kim A., Kuebler, Wolfgang M., Friedberg, Mark K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907585/
https://www.ncbi.nlm.nih.gov/pubmed/29599211
http://dx.doi.org/10.1161/JAHA.117.007928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907585/
https://www.ncbi.nlm.nih.gov/pubmed/29599211
http://dx.doi.org/10.1161/JAHA.117.007928

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