Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent

Antimonials (Sb) were used for decades for chemotherapy of visceral leishmaniasis (VL). Now abandoned in the Indian subcontinent (ISC) because of Leishmania donovani resistance, this drug offers a unique model for understanding drug resistance dynamics. In a previous phylogenomic study, we found two...

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Detalles Bibliográficos
Autores principales: Dumetz, F., Cuypers, B., Imamura, H., Zander, D., D’Haenens, E., Maes, I., Domagalska, M. A., Clos, J., Dujardin, J.-C., De Muylder, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907651/
https://www.ncbi.nlm.nih.gov/pubmed/29669889
http://dx.doi.org/10.1128/mSphere.00548-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907651/
https://www.ncbi.nlm.nih.gov/pubmed/29669889
http://dx.doi.org/10.1128/mSphere.00548-17

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