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Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent
Antimonials (Sb) were used for decades for chemotherapy of visceral leishmaniasis (VL). Now abandoned in the Indian subcontinent (ISC) because of Leishmania donovani resistance, this drug offers a unique model for understanding drug resistance dynamics. In a previous phylogenomic study, we found two...
Autores principales: | Dumetz, F., Cuypers, B., Imamura, H., Zander, D., D’Haenens, E., Maes, I., Domagalska, M. A., Clos, J., Dujardin, J.-C., De Muylder, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907651/ https://www.ncbi.nlm.nih.gov/pubmed/29669889 http://dx.doi.org/10.1128/mSphere.00548-17 |
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