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Impact of Long-Term Erythromycin Therapy on the Oropharyngeal Microbiome and Resistance Gene Reservoir in Non-Cystic Fibrosis Bronchiectasis

Long-term macrolide therapy reduces rates of pulmonary exacerbation in bronchiectasis. However, little is known about the potential for macrolide therapy to alter the composition and function of the oropharyngeal commensal microbiota or to increase the carriage of transmissible antimicrobial resista...

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Detalles Bibliográficos
Autores principales: Choo, Jocelyn M., Abell, Guy C. J., Thomson, Rachel, Morgan, Lucy, Waterer, Grant, Gordon, David L., Taylor, Steven L., Leong, Lex E. X., Wesselingh, Steve L., Burr, Lucy D., Rogers, Geraint B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907653/
https://www.ncbi.nlm.nih.gov/pubmed/29669883
http://dx.doi.org/10.1128/mSphere.00103-18