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Synergistic antitumor effects of cMet inhibitor in combination with anti-VEGF in colorectal cancer patient-derived xenograft models

cMet signaling pathway is involved in the resistance to anti-VEGF therapy and cMet overexpression is associated with tumor progression and poor prognosis. In this study, the expression of cMet in 146 Chinese colorectal cancer (CRC) patients was examined by immunohistochemistry staining. Our data dem...

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Detalles Bibliográficos
Autores principales: Chen, Xiangheng, Guan, Zhonghai, Lu, Jun, Wang, Haohao, Zuo, Zhongkun, Ye, Fei, Huang, Jiangsheng, Teng, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907669/
https://www.ncbi.nlm.nih.gov/pubmed/29675102
http://dx.doi.org/10.7150/jca.20964