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Synergistic antitumor effects of cMet inhibitor in combination with anti-VEGF in colorectal cancer patient-derived xenograft models
cMet signaling pathway is involved in the resistance to anti-VEGF therapy and cMet overexpression is associated with tumor progression and poor prognosis. In this study, the expression of cMet in 146 Chinese colorectal cancer (CRC) patients was examined by immunohistochemistry staining. Our data dem...
Autores principales: | Chen, Xiangheng, Guan, Zhonghai, Lu, Jun, Wang, Haohao, Zuo, Zhongkun, Ye, Fei, Huang, Jiangsheng, Teng, Lisong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907669/ https://www.ncbi.nlm.nih.gov/pubmed/29675102 http://dx.doi.org/10.7150/jca.20964 |
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