Increased AURKA Gene Copy Number Correlates with Poor Prognosis and Predicts the Efficacy of High-dose Interferon Therapy in Acral Melanoma

Background: AURKA kinase is an essential serine/threonine kinase for mitosis and chromosome stability. The aberrant amplification and overexpression of AURKA are commonly observed in various types of cancer, including cutaneous melanoma. However, the status and the clinical significance of AURKA cop...

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Detalles Bibliográficos
Autores principales: Yan, Junya, Yu, Jiayi, Wu, Xiaowen, Xu, Tianxiao, Yu, Huan, Dai, Jie, Ma, Meng, Tang, Huan, Xu, Longwen, Chi, Zhihong, Si, Lu, Sheng, Xinan, Cui, Chuanliang, Kong, Yan, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907675/
https://www.ncbi.nlm.nih.gov/pubmed/29675108
http://dx.doi.org/10.7150/jca.24013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907675/
https://www.ncbi.nlm.nih.gov/pubmed/29675108
http://dx.doi.org/10.7150/jca.24013

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