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Improved Expansion and In Vivo Function of Patient T Cells by a Serum-free Medium

Improvements to T cell culture systems that promote long-term engraftment and function of adoptively transferred T cells will likely result in superior clinical benefit to more individuals. To this end, we recently developed a chemically defined cell culture medium that robustly expands all T cell s...

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Detalles Bibliográficos
Autores principales: Medvec, Andrew R., Ecker, Christopher, Kong, Hong, Winters, Emily A., Glover, Joshua, Varela-Rohena, Angel, Riley, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907749/
https://www.ncbi.nlm.nih.gov/pubmed/29687031
http://dx.doi.org/10.1016/j.omtm.2017.11.001