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miR-221 suppression through nanoparticle-based miRNA delivery system for hepatocellular carcinoma therapy and its diagnosis as a potential biomarker

BACKGROUND: MicroRNA-221(miR-221) is frequently dysregulated in cancer. The purpose of this study was to explore whether miR-221 can be used as a potential diagnostic marker or therapeutic target for hepatocellular carcinoma (HCC). METHODS: In this study, we investigated whether miR-221 expression w...

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Detalles Bibliográficos
Autores principales: Li, Feng, Wang, Feiran, Zhu, Changlai, Wei, Qun, Zhang, Tianyi, Zhou, You Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907790/
https://www.ncbi.nlm.nih.gov/pubmed/29713162
http://dx.doi.org/10.2147/IJN.S157805