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Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
The co-translational targeting or insertion of secretory and membrane proteins into the endoplasmic reticulum (ER) is a key biological process mediated by the signal recognition particle (SRP). In eukaryotes, the SRP68–SRP72 (SRP68/72) heterodimer plays an essential role in protein translocation. Ho...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907831/ https://www.ncbi.nlm.nih.gov/pubmed/28369529 http://dx.doi.org/10.1093/jmcb/mjx010 |