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Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation

The co-translational targeting or insertion of secretory and membrane proteins into the endoplasmic reticulum (ER) is a key biological process mediated by the signal recognition particle (SRP). In eukaryotes, the SRP68–SRP72 (SRP68/72) heterodimer plays an essential role in protein translocation. Ho...

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Detalles Bibliográficos
Autores principales: Gao, Yina, Zhang, Qi, Lang, Yue, Liu, Yang, Dong, Xiaofei, Chen, Zhenhang, Tian, Wenli, Tang, Jun, Wu, Wei, Tong, Yufeng, Chen, Zhongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907831/
https://www.ncbi.nlm.nih.gov/pubmed/28369529
http://dx.doi.org/10.1093/jmcb/mjx010