Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila

Neuroligins (Nlgs) are transmembrane cell adhesion molecules playing essential roles in synapse development and function. Genetic mutations in neuroligin genes have been linked with some neurodevelopmental disorders such as autism. These mutated Nlgs are mostly retained in the endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Tu, Renjun, Qian, Jinjun, Rui, Menglong, Tao, Nana, Sun, Mingkuan, Zhuang, Yan, Lv, Huihui, Han, Junhai, Li, Moyi, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907836/
https://www.ncbi.nlm.nih.gov/pubmed/28498949
http://dx.doi.org/10.1093/jmcb/mjx015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907836/
https://www.ncbi.nlm.nih.gov/pubmed/28498949
http://dx.doi.org/10.1093/jmcb/mjx015

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