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Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma

Despite extensive genetic diversity of HIV-1 in chronic infection, a single or few maternal virus variants become the founders of an infant’s infection. These transmitted/founder (T/F) variants are of particular interest, as a maternal or infant HIV vaccine should raise envelope (Env) specific IgG r...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Smith, Claire E. P., Giorgi, Elena E., Eudailey, Joshua, Martinez, David R., Yusim, Karina, Douglas, Ayooluwa O., Stamper, Lisa, McGuire, Erin, LaBranche, Celia C., Montefiori, David C., Fouda, Genevieve G., Gao, Feng, Permar, Sallie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908066/
https://www.ncbi.nlm.nih.gov/pubmed/29672607
http://dx.doi.org/10.1371/journal.ppat.1006944