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In vitro models of multiple system atrophy from primary cells to induced pluripotent stem cells

Multiple system atrophy (MSA) is a rare neurodegenerative disease with a fatal outcome. Nowadays, only symptomatic treatment is available for MSA patients. The hallmarks of the disease are glial cytoplasmic inclusions (GCIs), proteinaceous aggregates mainly composed of alpha‐synuclein, which accumul...

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Detalles Bibliográficos
Autores principales: Abati, Elena, Di Fonzo, Alessio, Corti, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908105/
https://www.ncbi.nlm.nih.gov/pubmed/29502349
http://dx.doi.org/10.1111/jcmm.13563