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Microtubule defects in mesenchymal stromal cells distinguish patients with Progressive Supranuclear Palsy

Progressive Supranuclear Palsy (PSP) is a rare neurodegenerative disease whose etiopathogenesis remains elusive. The intraneuronal accumulation of hyperphosphorylated Tau, a pivotal protein in regulating microtubules (MT), leads to include PSP into tauopathies. Pathological hallmarks are well known...

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Detalles Bibliográficos
Autores principales: Calogero, Alessandra Maria, Viganò, Mariele, Budelli, Silvia, Galimberti, Daniela, Fenoglio, Chiara, Cartelli, Daniele, Lazzari, Lorenza, Lehenkari, Petri, Canesi, Margherita, Giordano, Rosaria, Cappelletti, Graziella, Pezzoli, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908108/
https://www.ncbi.nlm.nih.gov/pubmed/29502334
http://dx.doi.org/10.1111/jcmm.13545