Cargando…

MicroRNA‐216a induces endothelial senescence and inflammation via Smad3/IκBα pathway

Vascular endothelial senescence contributes to atherosclerosis and coronary artery disease (CAD), but the mechanisms are yet to be clarified. We identified that microRNA‐216a (miR‐216a) significantly increased in senescent endothelial cells. The replicative senescence model of human umbilical vein e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Shujun, Mi, Xuenan, Chen, Yu, Feng, Congrui, Hou, Zhihui, Hui, Rutai, Zhang, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908109/
https://www.ncbi.nlm.nih.gov/pubmed/29512862
http://dx.doi.org/10.1111/jcmm.13567