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A novel peptide Phylloseptin‐PBu from Phyllomedusa burmeisteri possesses insulinotropic activity via potassium channel and GLP‐1 receptor signalling

Insulin, as one of the most important hormones regulating energy metabolism, plays an essential role in maintaining glucose and lipid homeostasis in vivo. Failure or insufficiency of insulin secretion from pancreatic beta‐cells increases glucose and free fatty acid level in circulation and subsequen...

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Detalles Bibliográficos
Autores principales: Long, Qilin, Wang, Lei, Zhou, Mei, Wu, Yuxin, Chen, Tianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908111/
https://www.ncbi.nlm.nih.gov/pubmed/29516672
http://dx.doi.org/10.1111/jcmm.13573