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Down‐regulation of PKM2 enhances anticancer efficiency of THP on bladder cancer

Pyruvate kinase M2 (PKM2) regulates the final step of glycolysis levels that are correlated with the sensitivity of anticancer chemotherapeutic drugs. THP is one of the major drugs used in non‐muscle‐invasive bladder cancer instillation chemotherapy. However, low response ratio of THP (19.7%) treatm...

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Detalles Bibliográficos
Autores principales: Su, Qiongli, Tao, Ting, Tang, Lei, Deng, Jun, Darko, Kwame Oteng, Zhou, Sichun, Peng, Mei, He, Shanping, Zeng, Qing, Chen, Alex F., Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908113/
https://www.ncbi.nlm.nih.gov/pubmed/29512924
http://dx.doi.org/10.1111/jcmm.13571