Cargando…

Caveolin‐1 down‐regulation is required for Wnt5a‐Frizzled 2 signalling in Ha‐Ras(V12)‐induced cell transformation

Caveolin‐1 (Cav1) is down‐regulated during MK4 (MDCK cells harbouring inducible Ha‐Ras (V12) gene) transformation by Ha‐Ras(V12). Cav1 overexpression abrogates the Ha‐Ras(V12)‐driven transformation of MK4 cells; however, the targeted down‐regulation of Cav1 is not sufficient to mimic this transforma...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Hsiu‐Kuan, Lin, Hsi‐Hui, Chiou, Yu‐Wei, Wu, Ching‐Lung, Chiu, Wen‐Tai, Tang, Ming‐Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908114/
https://www.ncbi.nlm.nih.gov/pubmed/29502342
http://dx.doi.org/10.1111/jcmm.13531