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Caveolin‐1 down‐regulation is required for Wnt5a‐Frizzled 2 signalling in Ha‐Ras(V12)‐induced cell transformation
Caveolin‐1 (Cav1) is down‐regulated during MK4 (MDCK cells harbouring inducible Ha‐Ras (V12) gene) transformation by Ha‐Ras(V12). Cav1 overexpression abrogates the Ha‐Ras(V12)‐driven transformation of MK4 cells; however, the targeted down‐regulation of Cav1 is not sufficient to mimic this transforma...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908114/ https://www.ncbi.nlm.nih.gov/pubmed/29502342 http://dx.doi.org/10.1111/jcmm.13531 |