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Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia

Cytokinesis failure leads to the emergence of tetraploid cells and multiple centrosomes. Chronic lymphocytic leukaemia (CLL) is the most common haematological malignancy in adults and is characterized by clonal B cell expansion. Here, we show that a significant number of peripheral blood CLL cells a...

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Detalles Bibliográficos
Autores principales: Rogne, Marie, Svaerd, Oksana, Madsen‐Østerbye, Julia, Hashim, Adnan, Tjønnfjord, Geir E., Staerk, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908127/
https://www.ncbi.nlm.nih.gov/pubmed/29516674
http://dx.doi.org/10.1111/jcmm.13579