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Propofol exposure during early gestation impairs learning and memory in rat offspring by inhibiting the acetylation of histone

Propofol is widely used in clinical practice, including non‐obstetric surgery in pregnant women. Previously, we found that propofol anaesthesia in maternal rats during the third trimester (E18) caused learning and memory impairment to the offspring rats, but how about the exposure during early pregn...

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Detalles Bibliográficos
Autores principales: Lin, Jiamei, Wang, Shengqiang, Feng, Yunlin, Zhao, Weihong, Zhao, Weilu, Luo, Foquan, Feng, Namin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908131/
https://www.ncbi.nlm.nih.gov/pubmed/29461008
http://dx.doi.org/10.1111/jcmm.13524