Cargando…

RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia

Leukemic cells often carry chromosome aberrations which generate chimeric genes of pathogenetic, diagnostic, and prognostic importance. New rearrangements giving rise to novel fusion genes define hitherto unrecognized genetic leukemia subgroups. G-banding, fluorescence in situ hybridization (FISH),...

Descripción completa

Detalles Bibliográficos
Autores principales: Panagopoulos, Ioannis, Gorunova, Ludmila, Jacobsen, Eva-Marie, Andersen, Kristin, Micci, Francesca, Heim, Sverre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908135/
https://www.ncbi.nlm.nih.gov/pubmed/29672642
http://dx.doi.org/10.1371/journal.pone.0196181