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RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia
Leukemic cells often carry chromosome aberrations which generate chimeric genes of pathogenetic, diagnostic, and prognostic importance. New rearrangements giving rise to novel fusion genes define hitherto unrecognized genetic leukemia subgroups. G-banding, fluorescence in situ hybridization (FISH),...
Autores principales: | Panagopoulos, Ioannis, Gorunova, Ludmila, Jacobsen, Eva-Marie, Andersen, Kristin, Micci, Francesca, Heim, Sverre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908135/ https://www.ncbi.nlm.nih.gov/pubmed/29672642 http://dx.doi.org/10.1371/journal.pone.0196181 |
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