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Epileptiform activity during inert gas euthanasia of mice

Carbon dioxide (CO(2)) is one of the most commonly used euthanasia agents for mice, yet it is highly aversive and nociceptive. Inert gases are a possible alternative, however there are qualitative reports of seizures resulting from exposure. Here we evaluate epileptiform activity caused by inert gas...

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Detalles Bibliográficos
Autores principales: Gent, Thomas C., Detotto, Carlotta, Vyssotski, Alexei L., Bettschart-Wolfensberger, Regula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908136/
https://www.ncbi.nlm.nih.gov/pubmed/29672545
http://dx.doi.org/10.1371/journal.pone.0195872