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Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968

DepR, a LysR-type transcriptional regulator encoded by the last gene of the putative min operon (orf21-20-19-depR) located at the downstream region of the anticancer agent FK228 biosynthetic gene cluster in Chromobacterium violaceum No. 968, positively regulates the biosynthesis of FK228. In this wo...

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Detalles Bibliográficos
Autores principales: Qiao, Yongjian, Tong, Tiantian, Xue, Jiao, Lin, Wenjing, Deng, Zixin, Cheng, Yi-Qiang, Zhu, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908139/
https://www.ncbi.nlm.nih.gov/pubmed/29672625
http://dx.doi.org/10.1371/journal.pone.0196173