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White matter alterations in the internal capsule and psychomotor impairment in melancholic depression

Emerging evidence suggests that structural brain abnormalities may play a role in the pathophysiology of melancholic depression. We set out to test whether diffusion-derived estimates of white matter structure were disrupted in melancholia in regions underpinning psychomotor function. We hypothesize...

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Detalles Bibliográficos
Autores principales: Hyett, Matthew P., Perry, Alistair, Breakspear, Michael, Wen, Wei, Parker, Gordon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908181/
https://www.ncbi.nlm.nih.gov/pubmed/29672517
http://dx.doi.org/10.1371/journal.pone.0195672