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A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines

Practice-changing culturing techniques of hepatocytes are highly required to increase their differentiation. Previously, we found that human liver cell lines HepaRG and C3A acquire higher functionality and increased mitochondrial biogenesis when cultured in the AMC-Bioartificial liver (BAL). Dynamic...

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Detalles Bibliográficos
Autores principales: Adam, Aziza A. A., van der Mark, Vincent A., Donkers, Joanne M., Wildenberg, Manon E., Oude Elferink, Ronald P. J., Chamuleau, Robert A. F. M., Hoekstra, Ruurdtje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908182/
https://www.ncbi.nlm.nih.gov/pubmed/29672606
http://dx.doi.org/10.1371/journal.pone.0193664