Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

Transcription activation domains (ADs) are inherently disordered proteins that often target multiple coactivator complexes, but the specificity of these interactions is not understood. Efficient transcription activation by yeast Gcn4 requires its tandem ADs and four activator-binding domains (ABDs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Tuttle, Lisa M., Pacheco, Derek, Warfield, Linda, Luo, Jie, Ranish, Jeff, Hahn, Steven, Klevit, Rachel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908246/
https://www.ncbi.nlm.nih.gov/pubmed/29562181
http://dx.doi.org/10.1016/j.celrep.2018.02.097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908246/
https://www.ncbi.nlm.nih.gov/pubmed/29562181
http://dx.doi.org/10.1016/j.celrep.2018.02.097

Ejemplares similares