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A novel occludin-targeting monoclonal antibody prevents hepatitis C virus infection in vitro

Since hepatitis C virus (HCV) is thought to enter into host hepatocytes using the same cellular pathways regardless of the genotypes, the host factors are promising targets to prevent and treat HCV infection. Human occludin (hOCLN) is one representative entry factor, and its second extracellular loo...

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Detalles Bibliográficos
Autores principales: Okai, Ken, Ichikawa-Tomikawa, Naoki, Saito, Akira C., Watabe, Tetsuya, Sugimoto, Kotaro, Fujita, Daiki, Ono, Chikako, Fukuhara, Takasuke, Matsuura, Yoshiharu, Ohira, Hiromasa, Chiba, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908272/
https://www.ncbi.nlm.nih.gov/pubmed/29682171
http://dx.doi.org/10.18632/oncotarget.24742