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ATM/RB1 mutations predict shorter overall survival in urothelial cancer

BACKGROUND: Mutations of DNA repair genes, e.g. ATM/RB1, are frequently found in urothelial cancer (UC) and have been associated with better response to cisplatin-based chemotherapy. Further external validation of the prognostic value of ATM/RB1 mutations in UC can inform clinical decision making an...

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Detalles Bibliográficos
Autores principales: Yin, Ming, Grivas, Petros, Emamekhoo, Hamid, Mendiratta, Prateek, Ali, Siraj, Hsu, JoAnn, Vasekar, Monali, Drabick, Joseph J., Pal, Sumanta, Joshi, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908293/
https://www.ncbi.nlm.nih.gov/pubmed/29682192
http://dx.doi.org/10.18632/oncotarget.24738