Testosterone metabolites inhibit proliferation of castration- and therapy-resistant prostate cancer

Novel treatments for castration-resistant prostate cancer (CRPC) such as abiraterone acetate (AA) or enzalutamide effectively target the androgen pathway to arrest aberrant signalling and cell proliferation. Testosterone is able to inhibit tumour cell growth in CRPC. Estrogen receptor-beta (ERβ) bin...

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Detalles Bibliográficos
Autores principales: Bremmer, Felix, Jarry, Hubertus, Unterkircher, Valerie, Kaulfuss, Silke, Burfeind, Peter, Radzun, Heinz-Joachim, Ströbel, Philipp, Thelen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908297/
https://www.ncbi.nlm.nih.gov/pubmed/29682196
http://dx.doi.org/10.18632/oncotarget.24763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908297/
https://www.ncbi.nlm.nih.gov/pubmed/29682196
http://dx.doi.org/10.18632/oncotarget.24763

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