Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer

Development of resistance to standard therapies complicates treatment of advanced prostate cancer. Alternative splicing variants of the androgen receptor (AR), e.g. AR-V7 can mediate resistance to AR-targeting substances abiraterone and enzalutamide. Semi-synthetic marine natural compound rhizochali...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Otte, Katharina, Tabakmakher, Kseniya M., Hauschild, Jessica, Makarieva, Tatyana N., Shubina, Larisa K., Fedorov, Sergey N., Bokemeyer, Carsten, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908298/
https://www.ncbi.nlm.nih.gov/pubmed/29682197
http://dx.doi.org/10.18632/oncotarget.24764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908298/
https://www.ncbi.nlm.nih.gov/pubmed/29682197
http://dx.doi.org/10.18632/oncotarget.24764

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