Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells

Ferric chelates may be used as oral iron supplements or phosphate binders but both ferric citrate and ferric EDTA have been shown to promote tumor burden in murine models of colon cancer. Here we studied their effects on cancer cell growth, at typical supplemental iron levels encountered in the gast...

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Detalles Bibliográficos
Autores principales: Scheers, Nathalie M., Pereira, Dora I.A., Faria, Nuno, Powell, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908306/
https://www.ncbi.nlm.nih.gov/pubmed/29682205
http://dx.doi.org/10.18632/oncotarget.24899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908306/
https://www.ncbi.nlm.nih.gov/pubmed/29682205
http://dx.doi.org/10.18632/oncotarget.24899

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