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Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells
Ferric chelates may be used as oral iron supplements or phosphate binders but both ferric citrate and ferric EDTA have been shown to promote tumor burden in murine models of colon cancer. Here we studied their effects on cancer cell growth, at typical supplemental iron levels encountered in the gast...
Autores principales: | Scheers, Nathalie M., Pereira, Dora I.A., Faria, Nuno, Powell, Jonathan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908306/ https://www.ncbi.nlm.nih.gov/pubmed/29682205 http://dx.doi.org/10.18632/oncotarget.24899 |
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