Copy number changes at 8p11-12 predict adverse clinical outcome and chemo- and radiotherapy response in breast cancer

PURPOSE: The short arm of chromosome 8 (8p) is a frequent target of loss of heterozygosity (LOH) in cancer, and 8p LOH is commonly associated with a more aggressive tumor phenotype. The 8p11-12 region is a recurrent breakpoint area characterized by a sharp decrease in gains/amplifications and increa...

Descripción completa

Detalles Bibliográficos
Autores principales: Moelans, Cathy B., van Maldegem, Caroline M. G., van der Wall, Elsken, van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908307/
https://www.ncbi.nlm.nih.gov/pubmed/29682206
http://dx.doi.org/10.18632/oncotarget.24904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908307/
https://www.ncbi.nlm.nih.gov/pubmed/29682206
http://dx.doi.org/10.18632/oncotarget.24904

Ejemplares similares