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Runx2/Osterix and Zinc Uptake Synergize to Orchestrate Osteogenic Differentiation and Citrate Containing Bone Apatite Formation

Citrate is essential to biomineralization of the bone especially as an integral part of apatite nanocomposite. Citrate precipitate of apatite is hypothesized to be derived from mesenchymal stem/stromal cells (MSCs) upon differentiation into mature osteoblasts. Based on (13)C‐labeled signals identifi...

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Detalles Bibliográficos
Autores principales: Fu, Xuekun, Li, Yunyan, Huang, Tongling, Yu, Zhiwu, Ma, Kun, Yang, Meng, Liu, Qingli, Pan, Haobo, Wang, Huaiyu, Wang, Junfeng, Guan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908346/
https://www.ncbi.nlm.nih.gov/pubmed/29721422
http://dx.doi.org/10.1002/advs.201700755