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Glial alterations in human prion diseases: A correlative study of astroglia, reactive microglia, protein deposition, and neuropathological lesions

BACKGROUND: Neuroinflammation has recently been proposed to be a major component of neurodegenerative diseases. The aim of this study was to determine how the interaction between microglia and astroglia, which are the primary immune cell populations in the brain, and pathological prion protein (PrPs...

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Detalles Bibliográficos
Autores principales: Monzón, Marta, Hernández, Rodrigo S., Garcés, Moisés, Sarasa, Rocío, Badiola, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908569/
https://www.ncbi.nlm.nih.gov/pubmed/29642165
http://dx.doi.org/10.1097/MD.0000000000010320