Ube2s stabilizes β-Catenin through K11-linked polyubiquitination to promote mesendoderm specification and colorectal cancer development

The canonical Wnt/β-Catenin signaling pathway is widely involved in regulating diverse biological processes. Dysregulation of the pathway results in severe consequences, such as developmental defects and malignant cancers. Here, we identified Ube2s as a novel activator of the Wnt/β-Catenin signaling...

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Detalles Bibliográficos
Autores principales: Li, Zhaoyan, Wang, Yan, Li, Yadan, Yin, Wanqi, Mo, Libin, Qian, Xianghao, Zhang, Yiran, Wang, Guifen, Bu, Fan, Zhang, Zhiling, Ren, Xiaofang, Zhu, Baochang, Niu, Chang, Xiao, Wei, Zhang, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908793/
https://www.ncbi.nlm.nih.gov/pubmed/29674637
http://dx.doi.org/10.1038/s41419-018-0451-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908793/
https://www.ncbi.nlm.nih.gov/pubmed/29674637
http://dx.doi.org/10.1038/s41419-018-0451-y

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