Cargando…

Pushing the resolution limit by correcting the Ewald sphere effect in single-particle Cryo-EM reconstructions

The Ewald sphere effect is generally neglected when using the Central Projection Theorem for cryo electron microscopy single-particle reconstructions. This can reduce the resolution of a reconstruction. Here we estimate the attainable resolution and report a “block-based” reconstruction method for e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Dongjie, Wang, Xiangxi, Fang, Qianglin, Van Etten, James L, Rossmann, Michael G, Rao, Zihe, Zhang, Xinzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908801/
https://www.ncbi.nlm.nih.gov/pubmed/29674632
http://dx.doi.org/10.1038/s41467-018-04051-9