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A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory

PURPOSE: An item response theory (IRT) pharmacometric framework is presented to characterize Functional Assessment of Cancer Therapy-Breast (FACT-B) data in locally-advanced or metastatic breast cancer patients treated with ado-trastuzumab emtansine (T-DM1) or capecitabine-plus-lapatinib. METHODS: I...

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Detalles Bibliográficos
Autores principales: Schindler, Emilie, Friberg, Lena E., Lum, Bertram L., Wang, Bei, Quartino, Angelica, Li, Chunze, Girish, Sandhya, Jin, Jin Y., Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908825/
https://www.ncbi.nlm.nih.gov/pubmed/29675616
http://dx.doi.org/10.1007/s11095-018-2403-8