Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APP(NL-F/NL-F) knock-in mice

Amyloid pathology occurs early in Alzheimer’s disease (AD), and has therefore been the focus of numerous studies. Transgenic mouse models have been instrumental to study amyloidosis, but observations might have been confounded by APP-overexpression artifacts. The current study investigated early fun...

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Detalles Bibliográficos
Autores principales: Shah, Disha, Latif-Hernandez, Amira, De Strooper, Bart, Saito, Takashi, Saido, Takaomi, Verhoye, Marleen, D’Hooge, Rudi, Van der Linden, Annemie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908850/
https://www.ncbi.nlm.nih.gov/pubmed/29674739
http://dx.doi.org/10.1038/s41598-018-24657-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908850/
https://www.ncbi.nlm.nih.gov/pubmed/29674739
http://dx.doi.org/10.1038/s41598-018-24657-9

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