Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets

Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum antigens in children with severe malaria would improve our understanding of vulnerability to severe malaria and how protective immunity develop...

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Detalles Bibliográficos
Autores principales: Travassos, Mark A., Niangaly, Amadou, Bailey, Jason A., Ouattara, Amed, Coulibaly, Drissa, Lyke, Kirsten E., Laurens, Matthew B., Pablo, Jozelyn, Jasinskas, Algis, Nakajima, Rie, Berry, Andrea A., Adams, Matthew, Jacob, Christopher G., Pike, Andrew, Takala-Harrison, Shannon, Liang, Li, Kouriba, Bourema, Kone, Abdoulaye K., Rowe, J. Alexandra, Moulds, JoAnn, Diallo, Dapa A., Doumbo, Ogobara K., Thera, Mahamadou A., Felgner, Philip L., Plowe, Christopher V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908851/
https://www.ncbi.nlm.nih.gov/pubmed/29674705
http://dx.doi.org/10.1038/s41598-018-24462-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908851/
https://www.ncbi.nlm.nih.gov/pubmed/29674705
http://dx.doi.org/10.1038/s41598-018-24462-4

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