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Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets
Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum antigens in children with severe malaria would improve our understanding of vulnerability to severe malaria and how protective immunity develop...
Autores principales: | Travassos, Mark A., Niangaly, Amadou, Bailey, Jason A., Ouattara, Amed, Coulibaly, Drissa, Lyke, Kirsten E., Laurens, Matthew B., Pablo, Jozelyn, Jasinskas, Algis, Nakajima, Rie, Berry, Andrea A., Adams, Matthew, Jacob, Christopher G., Pike, Andrew, Takala-Harrison, Shannon, Liang, Li, Kouriba, Bourema, Kone, Abdoulaye K., Rowe, J. Alexandra, Moulds, JoAnn, Diallo, Dapa A., Doumbo, Ogobara K., Thera, Mahamadou A., Felgner, Philip L., Plowe, Christopher V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908851/ https://www.ncbi.nlm.nih.gov/pubmed/29674705 http://dx.doi.org/10.1038/s41598-018-24462-4 |
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