Acute Hyperthermia Inhibits TGF-β1-induced Cardiac Fibroblast Activation via Suppression of Akt Signaling

Transforming growth factor-β1 (TGF-β1) induces phenotypic changes in fibroblasts to become myofibroblasts with increased production of extracellular matrix (ECM) components and cytokines. It is also known that excessive activation of myofibroblasts accelerates cardiac fibrosis, remodeling, and thus...

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Detalles Bibliográficos
Autores principales: Narikawa, Masatoshi, Umemura, Masanari, Tanaka, Ryo, Fujita, Takayuki, Yokoyama, Utako, Ishigami, Tomoaki, Kimura, Kazuo, Tamura, Kouichi, Ishikawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908876/
https://www.ncbi.nlm.nih.gov/pubmed/29674727
http://dx.doi.org/10.1038/s41598-018-24749-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908876/
https://www.ncbi.nlm.nih.gov/pubmed/29674727
http://dx.doi.org/10.1038/s41598-018-24749-6

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